30 de setembro de 2020

Decision-making deficits linked to real-life social dysfunction in crack cocaine-dependent individuals.

17 de março de 20111min

PubMed – Am J Addict. 2011 Jan;20(1):78-86. doi: 10.1111/j.1521-0391.2010.00097.x. Epub 2010 Nov 12.
Decision-making deficits linked to real-life social dysfunction in crack cocaine-dependent individuals.
Cunha PJ, Bechara A, de Andrade AG, Nicastri S.

Interdisciplinary Group of Studies on Alcohol and Drugs, Institute and Department of Psychiatry, University of São Paulo College of Medicine, São Paulo, Brazil. pjcunha@usp.br
Abstract
Crack cocaine-dependent individuals (CCDI) present abnormalities in both social adjustment and decision making, but few studies have examined this association. This study investigated cognitive and social performance of 30 subjects (CCDI × controls); CCDI were abstinent for 2 weeks. We used the Social Adjustment Scale (SAS), Wisconsin Card Sorting Test (WCST), and Iowa Gambling Task (IGT). Disadvantageous choices on the IGT were associated with higher levels of social dysfunction in CCDI, suggesting the ecological validity of the IGT. Social dysfunction and decision making may be linked to the same underlying prefrontal dysfunction, but the nature of this association should be further investigated. 

American Academy of Addiction Psychiatry.


Sobre a UNIAD

A Unidade de Pesquisa em álcool e Drogas (UNIAD) foi fundada em 1994 pelo Prof. Dr. Ronaldo Laranjeira e John Dunn, recém-chegados da Inglaterra. A criação contou, na época, com o apoio do Departamento de Psiquiatria da UNIFESP. Inicialmente (1994-1996) funcionou dentro do Complexo Hospital São Paulo, com o objetivo de atender funcionários dependentes.



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