Functional Connectivity in Brain Networks Underlying Cognitive Control in Chronic Cannabis Users
Ian H Harding, Nadia Solowij, Ben J Harrison, Michael Takagi, Valentina Lorenzetti1, Dan I Lubman4, Marc L Seal, Christos Pantelis and Murat Yu ̈cel
Little is yet known of the long-term consequences of cannabis use on brain function underlying cognitive-control abilities. Cognitive-control processes promote adaptive and dynamic goal-directed behavior by biasing perceptual and informa- tion processing within the brain in favor of stimuli and responses relevant to current goals (Botvinick et al, 2001; Ridderinkhof et al, 2004). These processes include the ability to focus and shift attention, to inhibit inappropriate behavioral responses, and to monitor and change one’s behavior in response to ongoing environmental feedback (MacDonald et al, 2000; Ridderinkhof et al, 2004; Suchy, 2009).