Clinical Impact, Reactogenicity, and Immunogenicity After the First CoronaVac Dose in Kidney Transplant Recipients

26 de julho de 20211min10
Kidneys operation puzzle

In phase-3 trial, inactivated SARS-CoV-2 vaccine (CoronaVac, Sinovac Life-Sciences, Beijing, China) was associated with 71.1% seroconversion at least 14-days after the 2nddose, showing 50.7% efficacy against symptomatic COVID-19 among healthcare workers. Currently this vaccine has been approved for emergency use in 24 countries, including Brazil, where the national vaccination program was launched on 01/Jan/2021 following the age criterion.

Kidney transplant recipients have shown 20-30% COVID-19-associated fatality rates, have been excluded in vaccine trials, and had no early priority for vaccination. Therefore, this single-center, prospective, 12-month follow-up study was designed to assess clinical impact, reactogenicity, and immunogenicity of CoronaVac.

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Sobre a UNIAD

A Unidade de Pesquisa em álcool e Drogas (UNIAD) foi fundada em 1994 pelo Prof. Dr. Ronaldo Laranjeira e John Dunn, recém-chegados da Inglaterra. A criação contou, na época, com o apoio do Departamento de Psiquiatria da UNIFESP. Inicialmente (1994-1996) funcionou dentro do Complexo Hospital São Paulo, com o objetivo de atender funcionários dependentes.


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