Alcohol-Attributable Cancer Deaths and Years of Potential Life Lost in the United States.

2 de março de 20133min1


Nelson DE, et al. Show all


Am J Public Health. 2013 Feb 14. [Epub ahead of print]


David E. Nelson and Paige Miller are with National Cancer Institute, Bethesda, MD. Dwayne W. Jarman is with Food and Drug Administration, Detroit, MI, and US Public Health Service, Rockville, MD. Jürgen Rehm and Kevin D. Shield are with Centre for Addiction and Mental Health, Toronto, Ontario. Thomas K. Greenfield, William C. Kerr, and Yu Ye are with Alcohol Research Group, Public Health Institute, Emeryville, CA. Grégoire Rey is with INSERM, CépiDc, Le Kremlin-Bicêtre, France. Timothy S. Naimi is with Boston University Medical Center, Boston, MA.


Objectives. Our goal was to provide current estimates of alcohol-attributable cancer mortality and years of potential life lost (YPLL) in the United States. Methods. We used 2 methods to calculate population-attributable fractions. We based relative risks on meta-analyses published since 2000, and adult alcohol consumption on data from the 2009 Alcohol Epidemiologic Data System, 2009 Behavioral Risk Factor Surveillance System, and 2009-2010 National Alcohol Survey. Results. Alcohol consumption resulted in an estimated 18 200 to 21 300 cancer deaths, or 3.2% to 3.7% of all US cancer deaths. The majority of alcohol-attributable female cancer deaths were from breast cancer (56% to 66%), whereas upper airway and esophageal cancer deaths were more common among men (53% to 71%). Alcohol-attributable cancers resulted in 17.0 to 19.1 YPLL for each death. Daily consumption of up to 20 grams of alcohol (≤ 1.5 drinks) accounted for 26% to 35% of alcohol-attributable cancer deaths. Conclusions. Alcohol remains a major contributor to cancer mortality and YPLL. Higher consumption increases risk but there is no safe threshold for alcohol and cancer risk. Reducing alcohol consumption is an important and underemphasized cancer prevention strategy. (Am J Public Health. Published online ahead of print February 14, 2013: e1-e8. doi:10.2105/AJPH.2012.301199).

Sobre a UNIAD

A Unidade de Pesquisa em álcool e Drogas (UNIAD) foi fundada em 1994 pelo Prof. Dr. Ronaldo Laranjeira e John Dunn, recém-chegados da Inglaterra. A criação contou, na época, com o apoio do Departamento de Psiquiatria da UNIFESP. Inicialmente (1994-1996) funcionou dentro do Complexo Hospital São Paulo, com o objetivo de atender funcionários dependentes.


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