AGE AT ONSET OF PSYCHOSIS IN PATIENTS WITH SCHIZOPHRE- NIA: EVIDENCE FOR A SEX-DEPENDENT INTERACTION BETWEEN BDNF VAL66MET GENOTYPE AND CANNABIS USE

2 de fevereiro de 20111min

Jeroen Decoster, Jim van Os, Gunter Kenis, Cécile Henquet, Joseph Peuskens, Marc De Hert, Ruud van Winkel

Background: Discovering modifiable predictors for age at onset may help to identify predictors of transition to psychosis in the ‘at- risk mental state’. Previous studies inconsistently reported main effects of sex, BDNF Val66Met and cannabis, suggesting more complex models may be required. A sex-specific model of gene- environment interaction between BDNF Val66Met and cannabis use, affecting age at onset of psychosis, was hypothesized.

sdarticle-2.pdf


Sobre a UNIAD

A Unidade de Pesquisa em álcool e Drogas (UNIAD) foi fundada em 1994 pelo Prof. Dr. Ronaldo Laranjeira e John Dunn, recém-chegados da Inglaterra. A criação contou, na época, com o apoio do Departamento de Psiquiatria da UNIFESP. Inicialmente (1994-1996) funcionou dentro do Complexo Hospital São Paulo, com o objetivo de atender funcionários dependentes.



Newsletter


WP2Social Auto Publish Powered By : XYZScripts.com